Investigation into patients with suspected adverse reactions to beta-lactams carried out by the allergy unit of Rio de Janeiro General Policlinic

Methods This study was a retrospective analysis of cases of patients referred to the Allergy Clinic of Rio de Janeiro General Policlinic with records of suggestive of AR to BL, in the period between February 2011 and July 2014. All the patients observed ENDA protocol: specific questionnaire of adverse drug reactions, IgE specific for penicillin G and V, amoxicillin and ampicillin, followed by skin prick tests (SPT) and intradermal (ID) with penicillin and amoxicillin. Finally, the provocation test (DTP) was carried out with Amoxicillin, each step being followed from the previous negative result.